Weight loss is harder than rocket science.

ghostshaper

Phil Edwards status
Jan 22, 2005
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On way to do it is to go super low calorie.

But that makes life horrible.

To slow aging lift weights.
Yeah, calorie restriction is one way. Sinclair promotes blood sugar regulation more heavily, where fasting comes in: Instead of eating constantly and having spikes in your blood sugar after food intake, your blood sugar level is evenly regulated by your liver while you're fasting. He also takes metformin (diabetes drug) to regulate his blood sugar.

Exercise is a huge component of slowing aging, of course.
 

ghostshaper

Phil Edwards status
Jan 22, 2005
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I wonder what Sinclairs workout program.

All the anti aging guys want to curb mTOR but you need it too.
Yeah, him being a geneticist, mTOR is one of 3 major epigenomic pathways he's interested in.

from NIH:
Abstract
The mammalian/mechanistic target of rapamycin (mTOR) is a key component of cellular metabolism that integrates nutrient sensing with cellular processes that fuel cell growth and proliferation. Although the involvement of the mTOR pathway in regulating life span and aging has been studied extensively in the last decade, the underpinning mechanisms remain elusive. In this review, we highlight the emerging insights that link mTOR to various processes related to aging, such as nutrient sensing, maintenance of proteostasis, autophagy, mitochondrial dysfunction, cellular senescence, and decline in stem cell function.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611156/
 

VonMeister

Duke status
Apr 26, 2013
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JOE BIDENS RAPE FINGER
Medical practitioners prescribe sarcopenia to people at a young age. You're not young anymore, just take it easy is common health advice from Dr's. The good news is that train of thought has been changing quickly and you see more and more docs advise strength training for the aged and aging.

Getting into the weeds on cellular activity is just another away to allow people to be convinced they are broken...look how many people really believe they are allergic to gluten.

Physical Therapists are the worst because they are supposed to be in the business of making people physically healthy .....but currently it's the least likely place where you will receive advice or instructions on how to get stronger and healthier. Look how many people think they are going something physically positive for them by doing yoga, which is a common subject for PT's mostly because they believe in the medical fallacy of stretching.

One interesting thing is the amount of chiropractors that won't do adjustments anymore is growing rapidly. The veil is off and it's accepted by Chiro's that aren't bad people that adjustments are purely mental (placebo) ...and knowing this they are doing other things (placebos) to give patients the confidence to resume activities. Not to mention adjustments have an element of danger to them and should be avoided.

Fat acceptance is poison.
 
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Autoprax

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Jan 24, 2011
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I think there is really powerful global effect to all the systems in the body by loading with heavy weights.

*Heavy is a relative term, of course.

You are sending a really potent survival signal that makes the body thrive.

Cold and heat send the same potent signal.
 
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VonMeister

Duke status
Apr 26, 2013
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JOE BIDENS RAPE FINGER
I think there is really powerful global effect to all the systems in the body by loading with heavy weights.

*Heavy is a relative term, of course.

You are sending is really potent survival signal that makes the body thrive.

Cold and heat send the same potent signal.
When I lift something heavier it's usually around a couple kilo's more than before and sometimes it's weeks or months before I get those kilos. When someone is new to strength training they will lift sometimes 10-20 kilos more than last time in a week. Relative for sure.
 
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