The magic number is 10%.Still, a shitload of people have an accident -> got hooked on that sweet pharma good good -> disaster arc.
Those people are addictive personalities waiting to get addicted too something.
The key for them is to get addicted to weight lifting or bike riding or studying.
If I couldn't do drugs because I had an addictive temperment, I would do ice baths and heat exposure.
That is such a killer high.