Dopamine is the main driver of our existence and has a direct effect on how you feel day to day and perceive the world; as the modern era is one of indulgence it's very easy to throw the system off balance. Addiction, smartphones, pornography, the layering of dopamine inducing activities, etc. Why certain activities lose their luster. Why wave pools suck. Why doing menial tasks is important. Why goal setting is important. Why you learn and why you don't. Why you feel empty and unfulfilled. How to feel better (stop stimulating your need for dopamine release). The content relates directly to how some people are suffering here. This is all science content, no soapboxing. Relevant especially in our present era, as we have more access to dopamine inducing activities than any other time in human history.
JP/Huberman:
0:00) Coming Up
(0:57) Intro
(3:18) Where anxiety stems from
(11:57) Flipping the autonomic response
(23:10) Power of the prefrontal cortex
(30:00) Accessing our alternate selves
(36:25) When you stimulate the Insular cortex
(42:08) The one true world currency
(46:38) Dopamine’s pleasure derives from anticipation
(50:10) Depressive cascades
(54:12) Assess errors by state, not trait
(1:01:45) Dopamine chases outer stimuli
(1:04:13) Can new stimuli rewrite our neural pathways?
(1:09:27) Manifesting and the dopamine cycle
(1:15:59) Adrenaline, micro-narratives
(1:20:33) Sustained attention and reward
(1:27:03) Zone of proximal development
(1:32:23) Resisting the easy dopamine hit, avoiding addiction
Huberman:
(00:00:00) Introduction & Tool 1 to Induce Lasting Dopamine
(00:04:48) Sponsors
(00:09:10) Upcoming (Zero-Cost) Neuroplasticity Seminar for Educators
(00:09:58) What Dopamine (Really) Does
(00:15:30) Two Main Neural Circuits for Dopamine
(00:18:14) How Dopamine Is Released: Locally and Broadly
(00:22:03) Fast and Slow Effects of Dopamine
(00:25:03) Dopamine Neurons Co-Release Glutamate
(00:28:00) Your Dopamine History Really Matters
(00:30:30) Parkinson’s & Drugs That Kill Dopamine Neurons. My Dopamine Experience
(00:36:58) Tool 3 Controlling Dopamine Peaks & Baselines
(00:40:06) Chocolate, Sex (Pursuit & Behavior), Nicotine, Cocaine, Amphetamine, Exercise
(00:46:46) Tool 4 Caffeine Increases Dopamine Receptors
(00:49:54) Pursuit, Excitement & Your “Dopamine Setpoint”
(00:56:46) Your Pleasure-Pain Balance & Defining “Pain”
(01:00:00) Addiction, Dopamine Depletion, & Replenishing Dopamine
(01:07:50) Tool 5 Ensure Your Best (Healthy) Dopamine Release
(01:15:28) Smart Phones: How They Alter Our Dopamine Circuits
(01:19:45) Stimulants & Spiking Dopamine: Counterproductive for Work, Exercise & Attention
(01:22:20) Caffeine Sources Matter: Yerba Mate & Dopamine Neuron Protection
(01:24:20) Caffeine & Neurotoxicity of MDMA
(01:26:15) Amphetamine, Cocaine & Detrimental Rewiring of Dopamine Circuits
(01:27:57) Ritalin, Adderall, (Ar)Modafinil: ADHD versus non-Prescription Uses
(01:28:45) Tool 6 Stimulating Long-Lasting Increases in Baseline Dopamine
(01:37:55) Tool 7 Tuning Your Dopamine for Ongoing Motivation
(01:47:40) Tool 8 Intermittent Fasting: Effects on Dopamine
(01:53:09) Validation of Your Pre-Existing Beliefs Increases Dopamine
(01:53:50) Tool 9 Quitting Sugar & Highly Palatable Foods: 48 Hours
(01:55:36) Pornography
(01:56:50) Wellbutrin & Depression & Anxiety
(01:58:30) Tool 10 Mucuna Pruriens, Prolactin, Sperm, Crash Warning
(02:01:45) Tool 11 L-Tyrosine: Dosages, Duration of Effects & Specificity
(02:05:20) Tool 12 Avoiding Melatonin Supplementation, & Avoiding Light 10pm-4am
(02:07:00) Tool 13 Phenylethylamine (with Alpha-GPC) For Dopamine Focus/Energy
(02:08:20) Tool 14 Huperzine A
(02:10:02) Social Connections, Oxytocin & Dopamine Release
(02:12:20) Direct & Indirect Effects: e.g., Maca; Synthesis & Application
(02:14:22) Zero-Cost & Other Ways To Support Podcast & Research
